The S/MIME feature in Open Ticket Request System (OTRS) before 2.2.5, and 2.3.x before 2.3.0-beta1, does not properly configure the RANDFILE environment variable for OpenSSL, which might make it easier for remote attackers to decrypt e-mail messages that had lower than intended entropy available for cryptographic operations, related to inability to write to the seeding file.

Open Ticket Request System (OTRS) before 2.3.0-beta4 checks for the rw permission, instead of the configured merge permission, during authorization of merge operations, which might allow remote authenticated users to bypass intended access restrictions by merging two tickets.

Kernel/System/Web/Request.pm in Open Ticket Request System (OTRS) before 2.3.2 creates a directory under /tmp/ with 1274 permissions, which might allow local users to bypass intended access restrictions via standard filesystem operations, related to incorrect interpretation of 0700 as a decimal value.

Multiple cross-site scripting (XSS) vulnerabilities in Open Ticket Request System (OTRS) before 2.3.3 allow remote attackers to inject arbitrary web script or HTML via vectors related to (1) AgentTicketMailbox or (2) CustomerTicketOverView.